Cardarine is a buzzword in the fitness world.

This compound was developed to help alleviate cardiovascular health ailments.

With time, however, it was noticed that Cardarine also had fat-burning and endurance-boosting properties.

In fact, it is so effective at enhancing physical performance that it is banned by both WADA and USADA.

This article is a guide to everything you need to know about Cardarine.

What is Cardarine SARM (GW1516)?

Cardarine is a research chemical and is often known as GW501516 or GW1516. It is often mistaken for a SARM because it yields similar effects.

However, Cardarine was developed in the early 90s through a collaboration between GlaxoSmithKline and Ligand Pharmaceuticals as a potential treatment for cardiovascular and metabolic disorders.

However, after numerous studies and trials, Cardarine’s development was halted in 2007 following a study that revealed that the compound had the potential to promote cancer development in rats.

Nevertheless, numerous athletes attest to Cardarine’s remarkable ability to boost cardiovascular health and fat loss. This has led to the widespread adoption of GW501516.

What is Cardarine Used For?

Cardarine development did not begin in the 90s as a matter of chance.

It was just emerging at this time that diabetes and heart disease could be attributed to a sedentary lifestyle.

Cardarine was developed to boost the rate of fat burning and to improve cardiovascular health.

In a nutshell, using Cardarine can help you to:

  • Burn fat quicker
  • Build muscle
  • Reduce inflammation
  • Improve heart and cardiovascular health

Is Cardarine (GW501516) a SARM?

As mentioned, Cardarine is often categorized along with SARMs, yet it is not one.

SARMs (Selective Androgen Receptor Modulators) are substances that work to increase the activity levels of androgens, such as testosterone in bone and muscle tissue.

Since testosterone is a muscle-building, as well as a fat-burning hormone, increasing its activity levels results in a significant boost in your muscle building and fat burning capacities.

Cardarine, on the other hand, has no effect whatsoever on the androgen receptors in your tissues. As such, it cannot be a SARM.

Part of the reason for Cardarine being confused for a SARM is the fact that it was introduced in the same period as SARMs.

Additionally, Ligand Pharmaceuticals – the company that created Cardarine – is also a manufacturer of SARMs, such as Ligandrol.

It also does not help that SARM vendors often include Cardarine in their SARM stacks. Nonetheless, SARMs and Cardarine are two entirely different compounds.

Cardarine Weight Loss – Burn Fat with GW501516

As mentioned, Cardarine was created to help solve metabolic-related disorders.

Part of that involves boosting metabolism, which is associated with an accelerated rate of fat burning and weight loss.

According to studies, a high or fast metabolism results in the body burning calories even when it is at rest. This means that few calories will be stored as fat.

How Does Cardarine Work in Fat Burning?

Cardarine works by activating lipolysis.

During lipolysis, the body starts breaking down stored fat into fatty acids for energy.

This effect benefits you in two ways – you get to burn stored fat, and you experience an increase in energy levels.

Cardarine Dosage: Cycles

As a result of the controversy surrounding this compound, the FDA does not recognize Cardarine as a dietary supplement. In fact, Cardarine is sold as a research chemical.

Consequently, no clinical studies have been conducted to determine the appropriate dosages.

As such, any dosage guidelines that you will find about Cardarine are based on anecdotal evidence derived from trial-and-error.

Most experienced users agree that the optimal Cardarine dosage is between 10 and 20 milligrams per day.

This compound has a half-life (the period when it is active in the body) of 12 hours. Therefore, to experience its full effects, it is recommended that you take the entire dose at once.

When it comes to cycling GW501516, experts recommend taking the compound for 12 consecutive weeks, and then taking a 6-week break before resuming.

Fortunately, you will not have to undergo post-cycle therapy because Cardarine is not a hormone.

While no one is yet to report any ill effects from using a higher dose, it is best to stick to the recommended dose of 20 milligrams.

Stacking Cardarine

Stacking refers to the art of using different types of supplements together to potentiate their effects.

This allows an individual to accelerate the rate at which their goals manifest. For example, if your goal is to lose weight, then stacking different fat-burning products could help you do so sooner.

While Cardarine is typically used as a weight-loss supplement, it also has muscle-building properties. Therefore, it can be used in both your cutting and bulking stacks.

A cutting stack is one that is designed to facilitate weight loss. A sample cutting stack involving Cardarine would look something like this:

  • 20 mg of Cardarine per day
  • 50 mg of Andarine per day
  • 25 mg of Ostarine per day

A muscle-building stack involving Cardarine, on the other hand, could look like this:

  • 10 mg of Cardarine per day
  • 10 mg of YK11 per day
  • 20 mg of Ligandrol per day

How Long Does Cardarine take to Work?

The effects of using Cardarine usually set in almost immediately.

This is why you are advised to time your dosage between 30 minutes and one hour before your workout. This will allow you to experience the boost in stamina and energy that you need for an effective workout.

When to take Cardarine (GW-1516)

As mentioned, the best time to take Cardarine is between 30 minutes and an hour before your workout.

What are Cardarine Benefits?

Studies are showing that this compound can yield several health benefits, including:

1. Improving Brain Health

Findings from studies involving mice reveal that Cardarine can improve blood circulation in the brain, thus resulting in improved brain function. Cardarine also seems to reduce oxidative stress in the brain.

2. Boosting the Rate of Fat Burning

As mentioned, one of the main motivations behind developing Cardarine was to increase the rate at which we burn fat.

In one study, a group of men with bad cholesterol profiles and high belly fat levels had Cardarine administered to them for six weeks.

Subsequent tests revealed they all experienced a significant reduction in their fatty acid, VLDL proteins, and triglyceride levels.

In another study involving inactive individuals, those who received Cardarine displayed a significant increase in their fat-burning ability.

3. Fighting Obesity

In a study involving overweight individuals, the participants who received Cardarine displayed significant improvements from metabolic syndrome symptoms.

Their blood fat levels decreased by up to 30%, their blood insulin levels reduced by 11%, while their liver fat levels dropped by to 20%.

In another study involving obese monkeys, those that received Cardarine displayed decreases in their insulin, LDL cholesterol, and triglyceride levels. Moreover, they showed increases in their HDL cholesterol levels.

Mice that had Cardarine administered to them showed an increase in their insulin sensitivity and started releasing less glucose from their liver.

If this effect can also occur in humans, Cardarine could be incredibly helpful in treating both type II diabetes and obesity.

4. Improving Heart Health

In addition to lowering cholesterol levels, Cardarine can also improve your heart health due to its effects on the blood vessels.

In a study involving mice, Cardarine was shown to prevent oxidative damage to their blood vessels.

Additionally, this compound can lower the risk of plaque building up in the arteries. Cardarine does that by boosting nitric oxide amounts in the blood.

Using Cardarine in low doses has also been shown to reduce the amount of inflammation in the arteries, as well as tissue damage in mice.

Additionally, it helps reduce the risk of heart disease and complications by clearing up blood vessels.

5. Kidney Health

Mice studies show that Cardarine can reduce the amount of inflammation in the kidneys.

Moreover, mice that received Cardarine also displayed a significant reduction in the activity levels of genes that are associated with kidney disease.

6. Antioxidant and Anti-inflammatory Properties

One of the effects that Cardarine has is suppressing inflammation.

Scientists believe that Cardarine does that by blocking the substances that increase the activity of inflammatory genes.

When used on the skin, Cardarine was shown to improve the rate at which diabetic wounds in rats healed, perhaps thanks to the reduced inflammation.

7. Preventing Liver Damage

Cardarine encourages the liver to switch its source of fuel from glucose to fatty acids, thus reducing the amount of sugar in the blood.

In mice studies, the animals that received Cardarine displayed significantly less liver damage after being fed a high-fructose diet, as compared to those that did not receive the compound.

8. Muscle Growth and Stamina

In another mice study, animals that received Cardarine displayed significant improvements in their muscle fiber development.

They also demonstrated improvements in their endurance levels.

What are Cardarine Side Effects?

Research by the Australian Department of Health shows that there are no known short-term side effects from using Cardarine.

Nonetheless, more research is needed to determine whether this compound has any long-term side effects.

Cardarine and Cancer: Does it Cause Cancer

As mentioned, the reason for Cardarine development being halted in 2007 was the study that came out revealing that the compound could accelerate the development of cancerous tumors in mice.

Nonetheless, there are zero reports linking Cardarine use to cancer, as of 2020.

Cardarine Lab Tests – Does Cardarine Pass Medical Tests

There are limited human trials involving Cardarine, thanks to the controversy surrounding this compound. However, the three documented trials show that Cardarine does not have negative effects on the human body.

Cardarine Before and After Customer Reviews

The following are some of the reports from Cardarine users on Reddit:

Amazing compound. 20 mg a day split 10mg morning and 10mg before evening workout.. by two weeks, could have sex indefinitely. No fatigue during extreme workouts. Increases in endurance and cardiovascular performance caused immediate strength gains to be had during weight training. Literally feels like this.. I do an hour and a half and go as hard as I can with ease.. have to make myself not just stay to do another day’s workout. Notes: although it allowed for this level of performance and endurance, the body is still in need of the immense recovery associated with such a leap in performance
– Scorchedurple 

I’m currently running Cardarine and MK677 3 wks in, and I feel like a beast. I have RAD 140 on deck just hesitating on pulling the trigger if MK & GW make feel like a beast can’t imagine what RAD would make feel like. Just need to make sure everything is truly in order before I go down that road. Dosage 10mg GW 25mg MK. If head down the RAD highway .5mg- 7.5mg would be my dosage
– brokeazzgainz 

On it for 2 weeks now, 20mg, and it’s awesome. My energy is through the roof. it’s not something you can feel until you get deep into a set or your 5-10 min into cardio, after that it’s endless energy.”
- gobs4life

Cardarine for Sale: Where to Buy Cardarine

As mentioned, Cardarine is typically sold along with SARMs. Therefore, the best place to find Cardarine is from a reputable SARMs provider.

Finding a reputable and reliable SARMs provider, however, will take a bit of research on your part. Therefore, make sure that you first check out online reviews about a vendor before you purchase from them.

Online forums, such as Reddit, should be some of the first places to check out when looking for information about a SARMs provider.

Is Cardarine Legal?

Yes, you can buy, sell, or possess Cardarine legally, as long as it is for research purposes.

This is because the government recognizes Cardarine as a research chemical, but not a dietary supplement. Therefore, selling Cardarine as a dietary supplement, or labeling it as fit for human consumption is what is illegal.

Additionally, you cannot use Cardarine when preparing for professional sports, as WADA and USADA have this compound in their list of banned substances.

Nonetheless, as a consumer, you are not likely to get into trouble for purchasing and owning this compound. Companies that sell Cardarine as a legal supplement are the ones that are most likely to get into trouble.

Is Cardarine Legit?

Cardarine is a research compound that has been shown to have numerous performance-enhancing capabilities, as well as health benefits.

However, since the government does not recognize this compound as fit for human consumption, there have not been enough clinical trials and studies done to determine its full range of effects.

However, anecdotal evidence from numerous user reports shows that Cardarine is especially effective at alleviating the symptoms of metabolic disorders.

It boosts metabolism to help you burn fat, lose weight, and enhance your endurance.

Studies also show that Cardarine helps improve brain, heart, liver, kidney, and cardiovascular health.


How Much Does a Cardarine Cycle Cost?

Depending on your vendor, as well as your dosage amounts, a Cardarine cycle might cost between $45 and $70.

Is there Cardarine for Women?

Cardarine is designed to help anyone looking to boost their metabolism and get the associated benefits. Therefore, women can also benefit from using this compound. However, there isn’t a specific Cardarine product from women.

How Do You Stack Cardarine?

You can stack Cardarine with either cutting or bulking SARMs, depending on your goals. However, Cardarine is typically utilized in cutting stacks, thanks to its powerful fat-burning properties.

How Long Before a Workout Should I take Cardarine?

Consider taking your Cardarine dose 30 to 60 minutes before your workout.

Is Cardarine Useful When Bulking?

Studies show that Cardarine also has muscle-building properties. Therefore, it can be useful when looking to bulk.

Do You Take Cardarine Orally or Inject?

Cardarine usually comes in the form of powder in capsules. Therefore, it is taken orally.

What is the Formula for Cardarine?

The chemical formula for Cardarine is as follows: C21H18F3NO3S2.

Can You Use Cardarine Post Workout?

Since Cardarine works to boost your endurance, it makes more sense to use it as a pre-workout supplement.

Is Cardarine a Stimulant?

Cardarine might have the effects of a stimulant; however, it is not one.

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